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Melatonin & 5-HTP for more Restful Sleep

restful sleepby Dr Mercola

An estimated 40 percent of Americans are sleep deprived, according to the documentary “Sleepless in America,” with many getting less than five hours of sleep per night.

There are many reasons for this, from intentionally staying up late to watch TV or surf the web to health problems (like pain) that keep you awake.

Millions of Americans struggle to fall asleep each night, including about 10 percent who suffer from chronic insomnia. This latter condition involves difficulty falling asleep and staying asleep, as well as waking up too early in the morning.

In many cases, making changes to your sleep-hygiene routine and lifestyle, such as exercising more and avoiding exposure to blue light at night, can significantly improve your sleep.

However, if you feel like you’ve tried virtually everything and you’re still struggling to get a restful night’s sleep, it might be time to consider two natural supplements, melatonin and 5-hydroxytryptophan (5-HTP).

Why Melatonin Is Important for Sound Sleep
Your brain typically starts secreting the hormone melatonin around 9 or 10 p.m., which makes you sleepy. These regularly occurring secretions help regulate your sleep cycle as well as provide other important health benefits, including helping to prevent cancer.

Melatonin acts as a marker of your circadian phase or biological timing. In a nutshell, this hormone influences what time of day or night your body thinks it is, regardless of what time the clock on the wall displays.

Melatonin is produced by a pea-sized gland in the middle of your brain called the pineal gland.

In a normal night’s sleep, your melatonin levels stay elevated for about 12 hours. Then, as the sun rises, your pineal gland reduces your production of melatonin, and the levels in your blood decrease until they’re hardly measurable at all.

When your circadian rhythms are disrupted, such as from shift work, jet lag or nighttime light exposure, your body produces less melatonin.

Melatonin deficiency may come with some profound biological disadvantages, such as higher levels of inflammation, a weakened immune system, and an increased risk of cancer.

Who May Benefit From Melatonin Supplements?
It is best to encourage your body to produce its own melatonin. Your pineal gland produces melatonin roughly in approximation to the contrast of bright sun exposure in the day and complete darkness at night.

If you are in darkness all day long, it can’t appreciate the difference and will not optimize your melatonin production.

So one of the best ways to increase your melatonin production naturally is to get exposure to bright sunlight during the day and sleep in complete blackness at night. Supplementation may be beneficial in some cases, particularly if your circadian rhythm is off (such as from jet lag).

More Is Not Typically Better With Melatonin Supplementation
As for dosage, the researchers noted, “Daily doses of melatonin between 0.5 and 5 mg [milligrams] are similarly effective, except that people fall asleep faster and sleep better after 5 mg than 0.5 mg. Doses above 5 mg appear to be no more effective.”

In a study looking into the use of melatonin for primary sleep disorders, the supplement also appeared safe and effective, working to decrease the time it takes to fall asleep and improve total sleep time and quality.3

Keep in mind that only a very small dose is required — typically 0.25 mg or 0.5 mg to start with, and you can adjust it up from there.

Taking higher doses, such as 3 mg, can sometimes make you more wakeful instead of sleepier, so adjust your dose carefully and, ideally, under the guidance of a holistic health care practitioner.

In addition, melatonin supplementation may be most effective in people with low melatonin levels. If your levels are optimized, you may not experience additional sleep benefits from added supplementation.

What Is 5-HTP and How Does It Affect Sleep?
Your body produces 5-HTP (5-hydroxytryptophan) from the amino acid tryptophan (found in foods like poultry, eggs and cheese).

However, eating tryptophan-rich foods is not likely to significantly increase your 5-HTP levels, so 5-HTP supplements (which are made from extracts of the seeds of the African tree Griffonia simplicifolia) are sometimes used.

The chemical 5-HTP works in your brain and central nervous system by promoting the production of the neurotransmitter serotonin, and thereby may help boost mood and enhance sleep.

In one study, an amino acid preparation containing both GABA (a calming neurotransmitter) and 5-HTP reduced time to fall asleep, increased the duration of sleep and improved sleep quality.6 Further, as noted by the University of Maryland Medical Center:7

“In one study, people who took 5-HTP went to sleep quicker and slept more deeply than those who took a placebo. Researchers recommend 200 to 400 mg at night to stimulate serotonin, but it may take six to 12 weeks to be fully effective.”

There may be some beneficial “side effects” to 5-HTP as well. Research suggests the supplement naturally reduces appetite and food intake (including reduced carbohydrate consumption) and is associated with significant weight loss.8

Another study found 5-HTP led to significant improvements in symptoms of fibromyalgia as well, with only mild and transient side effects reported.9 The anti-depressant properties of 5-HTP are also of interest, and preliminary research suggests it may work as well as certain antidepressants in people with mild to moderate depression.

Try Natural Sleep Aids Before Sleeping Pills
Natural sleep aids work with your body’s natural circadian rhythm to help you get truly restful sleep. This is not the case with prescription sleeping pills. A study in 2012 revealed that people who take sleeping pills are not only at higher risk (by 35 percent) for certain cancers, but they are also nearly four times as likely to die as people who don’t take them. The list of health risks from sleeping pills includes:

  • Higher risk of death, including from accidents
  • Increased risk of cancer
  • Increased insulin resistance, food cravings, weight gain and diabetes
  • Complete amnesia, even from events that occurred during the day
  • Depression, confusion, disorientation, and hallucinations

Research involving data from more than 10,500 people who received drugs for poor sleep (including benzodiazepines) also showed that “as predicted, patients prescribed any hypnotic had substantially elevated hazards of dying compared to those prescribed no hypnotics.”

Try This First for Better Sleep Starting Tonight
f you’ve tried these steps and are still having trouble sleeping, you may want to consider melatonin or 5-HTP.

  • Avoid watching TV or using your computer in the evening, at least an hour or so before going to bed. These devices emit blue light, which tricks your brain into thinking it’s still daytime. Normally, your brain starts secreting melatonin between 9 and 10 p.m., and these devices emit light that may stifle that process.
  • Make sure you get BRIGHT sun exposure regularly. Your pineal gland produces melatonin roughly in approximation to the contrast of bright sun exposure in the day and complete darkness at night. If you are in darkness all day long, it can’t appreciate the difference and will not optimize your melatonin production.
  • Sleep in complete darkness, or as close to it as possible. The slightest bit of light in your bedroom can disrupt your body’s clock and your pineal gland’s melatonin production. Even the tiniest glow from your clock radio could be interfering with your sleep, so cover your radio up at night or get rid of it altogether.

Move all electrical devices at least 3 feet away from your bed. You may want to cover your windows with drapes or blackout shades. If this isn’t possible, wear an eye mask.

  • Install a low-wattage yellow, orange, or red light bulb if you need a source of light for navigation at night. Light in these bandwidths does not shut down melatonin production in the way that white and blue bandwidth light does. Salt lamps are handy for this purpose. You can also download a free application called f.lux that automatically dims your monitor or screens14 or use blue-light-blocking glasses.
  • Keep the temperature in your bedroom no higher than 70 degrees F. Many people keep their homes too warm (particularly their upstairs bedrooms). Studies show that the optimal room temperature for sleep is between 60 to 68 degrees F.
  • Take a hot bath 90 to 120 minutes before bedtime. This increases your core body temperature, and when you get out of the bath it abruptly drops, signaling your body that you are ready to sleep.
  • Avoid using loud alarm clocks. Being jolted awake each morning can be very stressful. If you are regularly getting enough sleep, you might not even need an alarm.
  • Get some sun in the morning, if possible. Your circadian system needs bright light to reset itself. Ten to 15 minutes of morning sunlight will send a strong message to your internal clock that day has arrived, making it less likely to be confused by weaker light signals during the night. More sunlight exposure is required as you age.
  • Be mindful of electromagnetic fields (EMFs) in your bedroom. EMFs can disrupt your pineal gland and its melatonin production, and may have other negative biological effects as well. A gauss meter is required if you want to measure EMF levels in various areas of your home. Ideally, you should turn off any wireless router while you are sleeping. You don’t need the Internet on when you are asleep.

For complete article and references: Mercola.com